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Every explainer in the hub — clinician-reviewed and written for people reading their own results.

Articles, page 3 of 4

A woman wrapped in a scarf holds a steaming mug on a sunny porch. Thyroid

Biomarker 101: Thyroid-stimulating hormone (TSH)

TSH is the pituitary’s instruction to the thyroid, which is why a high reading points to an underactive gland.

Clinician-reviewed·3 min read
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Anatomical illustration of a translucent torso with the thyroid gland glowing at the front of the neck. Thyroid

Biomarker 101: T4 (thyroxine)

T4 is the thyroid’s main output, and mostly inactive until the body converts it. Why free T4 tells you more than total T4.

Clinician-reviewed·3 min read
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Scientific illustration of the inside of a cell with glowing mitochondria producing energy. Thyroid

Biomarker 101: T3 (triiodothyronine)

T3 is the active thyroid hormone, and around 80 per cent of it is converted from T4 rather than made by the thyroid.

Clinician-reviewed·3 min read
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A mother smiles at her baby in a sunlit nursery filled with plants. Hormones

Biomarker 101: Prolactin

Known for lactation, but it also affects cycles, fertility and libido. Unusually easy to raise by accident.

Clinician-reviewed·3 min read
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Scientific illustration of a steroid hormone molecule rendered in soft pink and gold spheres. Hormones

Biomarker 101: Progesterone

Rises and falls dramatically across the cycle, so the day you test changes the result entirely.

Clinician-reviewed·3 min read
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A woman stretches on a sunny balcony full of plants with the beach beyond. Hormones

Biomarker 101: Oestrogen

What oestrogen regulates beyond reproduction - bone, mood, skin and cardiovascular function - and how levels shift with age.

Clinician-reviewed·3 min read
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Anatomical illustration of a translucent female pelvis with one ovary glowing as an egg is released. Fertility

Biomarker 101: Luteinising hormone (LH)

LH triggers ovulation in women and testosterone production in men. Why it is always read next to FSH.

Clinician-reviewed·3 min read
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Tiny knitted baby booties sit on a sunny windowsill beside an orchid, with a beach outside. Fertility

Biomarker 101: Human chorionic gonadotropin (hCG)

The hormone pregnancy tests detect, and what a quantitative blood measurement adds over a urine test.

Clinician-reviewed·3 min read
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Scientific illustration of red blood cells with small sugar molecules attached to their surfaces. Metabolic health

Biomarker 101: HbA1c

A three-month average of blood glucose in a single number. Why it is steadier than a fasting reading - and when it is unreliable.

Clinician-reviewed·3 min read
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A smiling lab technician holds a rack of sample tubes in a bright, modern laboratory. General health

Biomarker 101: Globulin

Not one protein but a whole category, covering transport proteins and antibodies. The albumin ratio says more than the number.

Clinician-reviewed·3 min read
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Two friends laugh while pouring green smoothies in a sunny kitchen. General health

Biomarker 101: Gamma-glutamyl transferase (GGT)

Sensitive to alcohol, medications and bile flow. Why GGT is most useful read next to ALP rather than alone.

Clinician-reviewed·3 min read
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Anatomical illustration of a translucent female pelvis with both ovaries glowing. Fertility

Biomarker 101: Follicle-stimulating hormone (FSH)

FSH drives egg and sperm development, and rises predictably with age. Why the cycle day you test on changes everything.

Clinician-reviewed·3 min read
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Two people stretch on the grass after a run in a sunny park. Performance

Biomarker 101: Creatine kinase (CK)

An enzyme released when muscle is stressed. Why a hard session can push it far above the reference range.

Clinician-reviewed·3 min read
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Scientific illustration of an immune cell moving through tissue surrounded by signalling molecules. Immunity

Biomarker 101: C-reactive protein (CRP)

A general inflammation marker that rises with infection, injury or illness. What hs-CRP measures differently.

Clinician-reviewed·2 min read
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Two people hold hands across a sunny cafe table by the beach. Immunity

Biomarker 101: Antinuclear antibody (ANA)

A screening test for autoimmune investigation. Why a positive result is common in healthy people and often means very little.

Clinician-reviewed·3 min read
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Anatomical illustration of a translucent body with the skeleton glowing in soft gold. General health

Biomarker 101: Alkaline phosphatase (ALP)

An enzyme from two different places - liver and bone - which is why ALP is never read on its own.

Clinician-reviewed·3 min read
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Overhead view of a shared lunch of grilled fish, salad and grains on a sunny table. General health

Biomarker 101: Albumin

The most abundant protein in blood. It reflects liver, kidney and nutrition at once - and quietly changes how other results read.

Clinician-reviewed·3 min read
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A man chops fresh vegetables at a bright kitchen bench. General health

Biomarker 101: Alanine aminotransferase (ALT)

The liver enzyme most specific to liver cells. What raises it, from a heavy training week to a new supplement.

Clinician-reviewed·3 min read
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A man does pull-ups on an outdoor bar in a sunny park. Hormones

Biomarker 101: Testosterone and free testosterone

Total counts everything; free counts what is available to tissue. Why SHBG means the two can point different ways.

Clinician-reviewed·3 min read
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Scientific illustration of signalling molecules binding to receptors on a cell surface. Longevity

Biomarker 101: Insulin-like growth factor 1 (IGF-1)

A growth hormone proxy linked to muscle, recovery and ageing research. Why the "optimal" level is genuinely contested.

Clinician-reviewed·3 min read
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A woman sits at a sunny seaside table with a bowl of mussels and bread. Nutrition

Biomarker 101: Vitamin B12 and folate

Two vitamins doing overlapping work. Why testing one without the other can mask a deficiency that keeps progressing.

Clinician-reviewed·3 min read
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A woman sits on a grassy headland with her face tilted up to the morning sun. Nutrition

Biomarker 101: Vitamin D

Mostly made in skin from sunlight rather than obtained from food. Why levels swing by season and who is worth testing.

Clinician-reviewed·3 min read
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Milk is poured into a glass on a sunny breakfast table with a bowl of oats and fruit. Nutrition

Biomarker 101: Calcium

Tightly regulated regardless of intake. Why a blood calcium result says little about your diet or your bones.

Clinician-reviewed·3 min read
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A woman serves greens from a skillet at a bright table overlooking the beach. Nutrition

Biomarker 101: Iron studies

Ferritin, transferrin, serum iron and saturation describe different stages of the same process - and the pattern shows how far along it has gone.

Clinician-reviewed·3 min read
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Showing 24 of 79 articles.

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